BioNumerics is the only software platform to offer integrated analysis of all major applications in Bioinformatics: 1D electrophoresis gels, all kinds of chromatographic and spectrometric profiles, 2D protein gels, phenotype characters, microarrays, and sequences. The unique power of BioNumerics lies in its ability to combine information from various genomic and phenotypic sources into one global database and conduct conclusive analyses.

BioNumerics runs on industry leading database engines such as Oracle® and Microsoft® SQL ServerTM. With its integrated networking and client-server features, the software is the perfect backbone for universal data management and analysis within and between laboratories of any size.

1.) Unparalleled 1D gel and fingerprint analysis

2.)  Innovative 2D gel analysis with powerful databasing and querying
3.)   Comprehensive sequence and chromosome analysis 

4.) Exploration of high-throughput microarray and genechip expression data
5.)  Combined querying, mining and analysis of all aforementioned data types
6.)  Numerous supervised and unsupervised learning techniques and statistical tests

7.) A large number of free Plugins available for specialist applications, automation, advanced analysis tools, reporting, etc.

1.)  Unparalleled 1D gel and fingerprint analysis

2.)  Innovative 2D gel analysis with powerful databasing and querying
3.)  Comprehensive sequence and chromosome analysis 

4.)  Exploration of high-throughput microarray and genechip expression data
5.)  Combined querying, mining and analysis of all aforementioned data types
6.)  Numerous supervised and unsupervised learning techniques and statistical tests

7.) A large number of free Plugins available for specialist applications, automation, advanced analysis tools, reporting, etc.

 modules

The BioNumerics software offers a modular platform that can be customized to suite your biological data set. Choose between 5 Data modules and 5 Analysis modules. Each Data module can be combined with any or all Analysis modules. The separate descriptions for the modules list most, but not all functions and possibilities. Use the BioNumerics Configurator to personalize your BioNumerics platform exactly to your research needs. Please contact us for details on specific functionality or if you’re having trouble choosing the right modules suited for your applications.

Data modules

Fingerprint data module

All types of electrophoresis gels, sequencer trace files, MALDI profiles, spectrophotometric and chromatographic profiles, ...

Character data module

Commercial test panels, antibiotic resistance profiles, phenotypic and biochemical features, repeat numbers, allele numbers, microarray data, ...

Sequence data module

From Sanger sequencing chromatograms and next generation sequencing reads to fully featured and annotated sequences, up to genome size.

Trend data module

Kinetic data (multiple time-interval readings), real-time PCR, and all kinds of X-Y measurement series.

Whole Genome Map data module

Fast visualization and clustering of Whole Genome Maps (OpGen, Inc.) for epidemiological strain typing and characterization.

Analysis modules

Tree and Network Inference module

Dendrograms, phylogenetic trees, population modelling graphs, consensus trees and networks, cluster significance analysis, ...

Classifiers and Identification module

Database and identification project based screening. Similarity-based identification or using classifiers (e.g. Naive Bayesian classifier, Support Vector Machine, ...). Automated identification via decision networks.

Dimensioning and Matrix Mining module

Perform MDS, PCA, MANOVA, etc. Identify differentiating characters and perform two-way clustering of any matrix table of characters and entries.

Genome Analysis Tools module

Comparison of genomes and chromosomes, analysis of organization and functional behavior of genomes, metagenomics, alignment of multiple chromosomes and chromosome-based SNP analysis.

Audit Trails module

Digital signing, recording and versioning of any database object from logging only to full tracking, allows the software to be used in compliance with the strictest Good Manufacturing Practice regulations, including FDA 21 CFR Part 11.

General BioNumerics Seven functionality

Object-oriented relational multi-user database interface. Store information fields as text, number or date. Lock information fields or limit editing options by using pick lists. Easy drag & drop linkage of multiple experiments to database entries. Powerful search engine for combined database searches on information fields and experiment presence and/or contents (character values, sequences, ranges, bands, etc.). Create views to retrieve data from any database object. Store and manage database queries and external attachments. Multi-database system: each database can contain any combination of different experiment types. Create levels and dependencies for a richer hierarchical data structure. Share and exchange data between users, databases and laboratories. Set up BioNumerics as a central lab-wide and multi-user database and analysis platform.

BioNumerics Network Licenses

• Powerful network license solution! See also the detailed description of our licensing options.
• License limits. Network licenses are available for any number of users. Contact us for details and pricing.

Compatibility

• Operating system. BioNumerics is compatible with Windows XP SP3, Windows Vista, Windows 7 and Windows 8.
• Hardware. PC compatible with 1 GB of RAM and high resolution true-color graphics (1024x768 or higher)